Letrozole is an aromatase inhibitor commonly used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by lowering estrogen levels in the body, which can slow down or reverse the growth of certain types of breast tumors.
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Recommended Dosage
The typical dosage of Letrozole varies based on the indication and the patient’s individual circumstances. Below are the general guidelines:
- Initial Therapy: The usual starting dose for treating hormone receptor-positive breast cancer is 2.5 mg taken once daily.
- Duration of Treatment: Letrozole is often prescribed for a duration of five years, but this can vary based on response and tolerability.
- Concomitant Medications: Dosage may be adjusted if patients are taking other medications that affect the metabolism of Letrozole.
- Missed Doses: If a dose is missed, it should be taken as soon as remembered. However, if it’s almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double dose.
Considerations Before Use
Before starting Letrozole, patients should discuss the following considerations with their healthcare provider:
- Any history of liver disease or other significant health conditions.
- Current medications and any potential interactions.
- Possible side effects and management strategies.
Conclusion
Letrozole is an effective treatment option for certain types of breast cancer. Understanding the proper dosage and consulting with healthcare professionals can enhance treatment efficacy and safety.